Phenotyping Chronic Pelvic Pain Based on Latent Class Modeling of Physical Examination
Table 4
(a) ROC curve analysis of abdominal wall site pairings to predict membership into latent class 2 (High pain group). (b) ROC curve analysis of vulvar sites to predict membership into latent class 2 (High pain group). (c) ROC curve analysis of pelvic floor muscle site pairings to predict membership into latent class 2 (High pain group). (d) ROC curve analysis of vaginal vault site pairings to predict membership into latent class 2 (High pain group).
(a)
Testing sites
AUC
Optimal threshold
Specificity
Sensitivity
Median
95% CI
Median
95% CI
Left and right upper abdomen
0.966
1
0.8304
0.7887
0.8690
0.9535
0.9147
0.9845
Umbilicus, pubis, Pfannestiel incission, and above the pubis
0.947
3
0.8839
0.8482
0.8839
0.8605
0.7984
0.9147
Left and right middle abdomen
0.974
2
0.9464
0.9196
0.9702
0.9070
0.8527
0.9535
Between the iliac crest and the lower costal margin*
0.921
1
0.8378
0.7988
0.8679
0.9070
0.857
0.9535
Left and right lower abdomen
0.951
1
0.8006
0.7560
0.8423
0.9375
0.8906
0.9766
Left and right inguinal ligament*
0.897
2
0.8269
0.7851
0.8657
0.7969
0.7266
0.8672
Significantly different from best pair. The best pair or best examination site in each region is marked in bold.
(b)
Testing sites
AUC
Optimal threshold
Specificity
Sensitivity
Median
95% CI
Median
95% CI
Vulva 12:00*
0.866
2
0.7636
0.6545
0.8727
0.9330
0.9067
0.9569
Vulva 2:00*
0.844
1
0.7273
0.6000
0.8364
0.9211
0.8947
0.9450
Vulva 4:00*
0.854
1
0.7636
0.6545
0.8727
0.8517
0.8158
0.8852
Vulva 6:00
0.916
1
0.9091
0.8182
0.9818
0.8158
0.7775
0.8517
Vulva 8:00
0.930
3
0.8364
0.7273
0.9273
0.9402
0.9163
0.9617
Vulva 10:00
0.954
2
0.9455
0.8727
1.0000
0.9187
0.8923
0.9450
Significantly different from best site. The best pair or best examination site in each region is marked in bold.
(c)
Testing sites
AUC
Optimal threshold
Specificity
Sensitivity
Median
95% CI
Median
95% CI
Left and right obdurator internus
0.932
10
0.8968
0.8643
0.9292
0.8407
0.7699
0.9027
Left and right puborectalis
0.955
6
0.8703
0.8357
0.9049
0.9262
0.8770
0.9672
Left and right Iliococcygeus
0.948
6
0.8407
0.7994
0.8791
0.9292
0.8761
0.9735
Significantly different from best pair. The best pair or best examination site in each region is marked in bold.
(d)
Testing sites
AUC
Optimal threshold
Specificity
Sensitivity
Median
95% CI
Median
95% CI
Left and right uterosacral ligament
0.991
8
0.9635
0.9438
0.9803
0.9406
0.8911
0.9802
Left and right adnexal*
0.963
9
0.8986
0.8676
0.9296
0.9100
0.8500
0.9600
Significantly different from best pair. The best pair or best examination site in each region is marked in bold.
