Opioid Use in Fibromyalgia Is Associated with Negative Health Related Measures in a Prospective Cohort Study

Table 3

Results of Multivariate and Univariate tests of General Linear Model Repeated Measures.

Variable	Multivariate test—Wilk’s Lambda—𝐹			Between-Subject Effects—Main effect of Opioid status—𝐹			Interaction Opioid status * time
Function	𝐹	sig	Eta squared	𝐹	sig	Eta squared	𝐹	sig	Eta squared
FIQ	13.15	0.001	0.95	11.08	0.001	0.081	0.493	0.484	0.004
HAQ	3.651	0.58	0.028	5.246	0.024	0.039	6.716	0.011	0.049
Depression	50.169	0.001	0.280	2.554	0.112	0.019	0.538	0.464	0.004
Anxiety	13.167	0.001	0.093	0.800	0.373	0.006	0.181	0.671	0.001
VAS	4.420	0.037	0.033	5.434	0.021	0.041	0.632	0.428	0.005
PGA	2.264	0.135	0.017	8.231	0.005	0.060	0.377	0.540	0.003
McGill Total	13.102	0.001	0.093	9.905	0.002	0.072	2.046	0.155	0.016
Catastrophizing	24.048	0.001	0.159	1.015	0.316	0.008	0.295	0.588	0.002