Loss of Central Inhibition: Implications for Behavioral Hypersensitivity after Contusive Spinal Cord Injury in Rats

Figure 1

Significant increases in cutaneous allodynia on the hind paws were observed in the injured group when compared to noninjured controls. Compared to preinjury, baseline, and uninjured control withdrawal thresholds, the withdrawal responses for the injured group after SCI were significantly lower from 2 to 12 wks after SCI. Similar values were observed up to 12 wks after injury.