Loss of Central Inhibition: Implications for Behavioral Hypersensitivity after Contusive Spinal Cord Injury in Rats
Figure 5
Protein expression of the GABA synthesizing enzyme GAD65/67 as detected by immunoblotting. There was a decrease in GAD65/67 expression at all levels, both in the acute and chronic paradigms. However, the downregulation of GAD65/67 was most noticeable at 12 wks. In the earlier time point, especially above the injury site (T5/6), the expression of GAD65/67 decreased slightly but continued a steady decline at all of the other levels.
