Loss of Central Inhibition: Implications for Behavioral Hypersensitivity after Contusive Spinal Cord Injury in Rats

Figure 6

Protein expression of the glycine receptor GLRA3 as detected by immunoblotting. At 1 week as well as at 12 wks, the protein expression of GLRA3 had downregulated at all levels of the spinal cord, but most notably below the injury site. Acutely, GLRA3 values showed only a small decrease at T5/6. However, this downregulation became more apparent at the other three levels. The same pattern was seen in the chronic paradigm.