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Pain Research and Treatment
Volume 2015, Article ID 629382, 13 pages
Review Article

Evidence-Based Treatments for Adults with Migraine

Department of Neurology, Hull Royal Infirmary, Hull, UK

Received 17 October 2015; Accepted 9 December 2015

Academic Editor: Hartmut Göbel

Copyright © 2015 Rubesh Gooriah et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Migraine, a significantly disabling condition, is treated with acute and preventive medications. However, some individuals are refractory to standard treatments. Although there is a host of alternative management options available, these are not always backed by strong evidence. In fact, most of the drugs used in migraine were initially designed for other purposes. Whilst effective, the benefits from these medications are modest, reflecting the need for newer and migraine-specific therapeutic agents. In recent years, we have witnessed the emergence of novel treatments, of which noninvasive neuromodulation appears to be the most attractive given its ease of use and excellent tolerability profile. This paper reviews the evidence behind the available treatments for migraine.