Clinical Study

Quantitative Thermal Testing Profiles as a Predictor of Treatment Response to Topical Capsaicin in Patients with Localized Neuropathic Pain

Table 1

Demographic data according to treatment response.

VariableNonrespondersResponders value

Gender (female/male ratio)19/1213/110.28
Age (mean)60.26 (14.25)58.42 (13.28)0.62
DN4 score5.90 (1.37)5.39 (1.29)0.24
Pretreatment NPRS7.21 (1.20)6.89 (1.75)0.79
Posttreatment NPRS7.08 (1.29)2.92 (1.38)n.a.
Duration of improvement, months (mean)b72.89 n.a.
Type of PeNP
 CPSP1813
 PHN128
 Posttrauma01
 CRPS12

DN4 = Douleur Neuropathique 4 Questionnaire. NPRS = numerical pain rating scale (0–10). CPSP = chronic postsurgical pain. PHN = postherpetic neuralgia. CRPS = complex regional pain syndrome type I. n.a. = not applicable. Gender and type of PeNP for the whole patient sample. For the others, numbers are given as means. Standard deviation in parenthesis. a = calculated for 19 patients. The other 5 were excluded due to reporting > 6 months of improvement. b = nonresponders had no days of improvement, most of whom reported no improvement at all. c = posttrauma and CRPS were not taken into account for the analysis due to the small number of patients.