Clinical Study

Quantitative Thermal Testing Profiles as a Predictor of Treatment Response to Topical Capsaicin in Patients with Localized Neuropathic Pain

Table 2

Contingency table.

TotalNo improvementImprovement

PPV = 76%174Nonhomogenous (WST ≠ HPT)
NPV = 71%382711Homogenous (WST = HPT)
553124Total
E = 87%S = 54%
NLR = 0.52PLR = 4.2

Contingency table for the QTT profiles and patterns observed as a predictor of improvement after application of the capsaicin 8% patch. WST ≠ HPT: nonhomogenous results for warm sensation threshold and heat pain threshold in the peripheral neuropathic pain area versus the contralateral control area, with one measurement (either WST or HPT) showing a significant difference between the control and treatment areas while the other measurement (either WST or HPT) is not significantly different between the two sites. WST = HTP: both warm sensation threshold and heat pain threshold had homogenous test results in the pain and control areas: both were either significantly higher or lower, or neither was significantly different. S: sensibility. E: specificity. PPV: positive predictive value. NPV: negative predictive value. PLR: Positive Likelihood Ratio. NLR: Negative Likelihood Ratio. = 8.94 (). Fisher exact test (two tailed).