Effects of a Single Dose of Parecoxib on Inflammatory Response and Ischemic Tubular Injury Caused by Hemorrhagic Shock in Rats

Table 2

Cytokine levels in the supernatant renal tissue in each of the four groups of rats.

Parameter	Plc/NH ()	Pcx/NH ()	Plc/H ()	Pcx/H ()
IL-1α	17.3 ± 4.2	16.7 ± 3.7	14.2 ± 4.1	17.3 ± 6.1
IL-1β	3.7 ± 1.2	3.7 ± 1.1	4.0 ± 0.6	3.8 ± 1.3
IL-6	44.6 ± 17.6	42.9 ± 15.8	43.5 ± 11.4	44.8 ± 20.3
IL-10	129.7 ± 37.5	131.1 ± 32.0	142.4 ± 23.0	137.8 ± 48.7
TNF-α	9.1 ± 3.9	8.8 ± 4.5	9.3 ± 3.0	10.0 ± 5.6

Data were expressed as picogram per milligram of protein. Values are means ± SD; n is number of animals. Plc/NH = placebo/no hemorrhage group, Pcx/NH = parecoxib/no hemorrhage group, Plc/H = placebo/hemorrhage group, and Pcx/H = parecoxib/hemorrhage group; .