Effects of a Single Dose of Parecoxib on Inflammatory Response and Ischemic Tubular Injury Caused by Hemorrhagic Shock in Rats

Table 3

Renal function values in each of the four groups of rats.

Parameter	Plc/NH ()	Pcx/NH ()	Plc/H ()	Pcx/H ()
(mL·min^−1)	0.018 ± 0.006	0.014 ± 0.006	0.008 ± 0.002	0.011 ± 0.003
(mL·min^−1)	0.003 ± 0.001	0.004 ± 0.001	0.002 ± 0.001	0.003 ± 0.001
FF	0.211 ± 0.135	0.320 ± 0.125	0.294 ± 0.192	0.294 ± 0.178
RVR (mmHg·min^−1·mL^−1)	4.906 ± 3.200	6.999 ± 2.680	12.027 ± 6.855	6.588 ± 3.070

Values are means ± SD; is number of animals. = clearance of sodium para-aminohippurate, = clearance of sodium iothalamate, FF = filtration fraction, RVR = renal vascular resistance, Plc/NH = placebo/no hemorrhage group, Pcx/NH = parecoxib/no hemorrhage group, Plc/H = placebo/hemorrhage group, and Pcx/H = parecoxib/hemorrhage group; Plc/NH > Plc/H and Pcx/H, and Pcx/NH > Plc/H, ; Pcx/NH > Plc/H, ; Plc/H > Plc/NH, .