|
First author and year | Number of patients | Method | Cure rate | Follow-up (mean) | Recurrence rate | Pros and cons |
|
Pressure relieving padding |
Travelute 2013 [25] | 10 | Self-adhering foam | 90% | Not reported | 0 | Retrospective. Follow-up not reported. |
Naqash 2013 [59] | 1 | Ear-padding | Pain resolved | 6 weeks | 0 | Case report. Short follow-up. |
Kuen-Spiegl 2011 [9] | 12 (18) | Bandage + foam plastic | 92% | 41–61 months | 25% (but discontinued treatment) | Prospective. 6 did not comply. |
Durrant 2011 [12] | 75 | Customized ear prosthesis | 74% | 52 months | 31% | Prospective. Confounder with topical steroid. |
Sanu 2007 [13] | 23 | Doughnut pillow | 57% | 12 months | 0 | Prospective. 7 did not comply. |
Moncrieff 2004 [26] | 15 | Foam-padding strapped to head | 87% | 18 weeks | 0 | Retrospective. Short follow-up. |
Timoney 2002 [14] | 12 | Different decompression methods | 92% | 24 months | 8% | Prospective. Used several methods. |
|
Topical nitroglycerin |
Sanz-Motilva 2015 [27] | 29 | 0,2% topical nitroglycerin | 93% | 5,9 months | 0,03% | Retrospective. Confounder with decompression. |
Colmenero 2014 [15] | 11 | Transdermal nitroglycerin patch | 64% | 3 months | 0 | Prospective. Lack of histology. |
Yélamos 2013 [48] | 1 | 2% nitroglycerin gel | Good effect | 4 months | 0 | Case report. |
Flynn 2011 [28] | 12 pt/13 lesions | 2% topical nitroglycerin | 92% | 2–13 months | 0 (within follow-up period) | Retrospective. Wide range of follow-up. |
|
Glucocorticoid injection |
Cox 2002 [29] | 60 | 1x triamcinolone intralesionally | 40% 3 months/33% long-term | 3–96 months | 6% | Retrospective. |
Lawrence 1991 [8] | 44 | Triamcinolone, 0,2–0,5 mL intralesionally + topical betamethasone 2 daily + lidocaine gel 2% before bed for 8 weeks | 27% at 8 weeks | 16 months (4,5–34) | Non-respondents went on to surgery. Respondents had 0 recurrence after 14 months | Prospective. Confounding therapies. |
Schmidt 1984 [36] | 3 | Local infiltration with Prednisolon-crystal-suspension, 3–6 inj. | 67% | 1 week after last treatment | Not reported | Case series. No follow-up after last treatment. |
Wade 1979 [16] | 8 | Intralesional inj. with triamcinolone | 100% | 0–12 months | 0 | Prospective. Unsure follow-up. |
|
Injectable collagen |
Greenbaum 1991 [17] | 5 | Collagen inj. over perichondrium | 100% | 16 months | 0 | Prospective. |
|