Table of Contents
Magnetic and Electrical Separation
Volume 10 (2000), Issue 3, Pages 141-159
http://dx.doi.org/10.1155/2000/83676

Novel Magnetic Microand Nanoparticles for Biomedical Separation and as Means for a New Approach to Aids Therapy

Institut für Anorganische Chemie, RWTH Aachen, Professor-Pirlet-Str. 1, Aachen D-52074, Germany

Received 26 January 2000; Accepted 2 February 2000

Copyright © 2000 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The separation principle and the advantage of using magnetic polymer particles in bioseparation is elucidated. After a short review of the presently used diverse magnetic microparticles as well as the basic differences of micro- and nanosized magnetic particles with regards to their physical properties in bio-separation, preparation and application of novel magnetic microparticles prepared from polyvinylalcohol are described. The performance of the novel product and their superior properties over established products in diverse bioseparation tests are shown. Furthermore, nanoparticles used for a new AIDS therapy approach are described. The basic principle is explained by which the AIDS virus (HIV) is destroyed through heat generated by inductively heated magnetic nanoparticles, which are specifically attached to the virus. Inductive heating tests with model magnetic colloids show that the required temperatures of > 50°C can easily be achieved.