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Volume 2006, Article ID 53901, 3 pages
Case Report

Synchronous Multifocal Osteosarcoma: Case Report and Literature Review

1Department of Orthopaedics, Bristol Royal Infirmary, United Bristol Healthcare NHS Trust, Bristol BS1 3NU, UK
2Avon Orthopaedics Centre, Southmead Hospital, North Bristol NHS Trust, Bristol BS16 1JE, UK
3Department of Orthopaedics, Weston General Hospital, Weston-Super-Mare BS23 4TQ, North Somerset, UK

Received 3 February 2006; Accepted 12 July 2006

Copyright © 2006 Verity A. Currall and John H. Dixon. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. Multifocal osteosarcoma is usually described as the occurrence of the tumour at two or more sites in a patient without pulmonary metastases and may be synchronous or metachronous. Case report. A previously well 21-year old male, who presented with a swollen, painful right knee with no history of trauma, was found to have a high-grade osteosarcoma of the distal tibia and proximal femur. He underwent resection and prosthetic replacement of the distal femur and proximal tibia and remains well 19 months after diagnosis. Discussion. Multifocal osteosarcoma is a rare condition with a poor prognosis. There is debate about whether it represents multiple primary tumours or metastatic disease.