Table of Contents Author Guidelines Submit a Manuscript
Volume 2006 (2006), Article ID 53901, 3 pages
Case Report

Synchronous Multifocal Osteosarcoma: Case Report and Literature Review

1Department of Orthopaedics, Bristol Royal Infirmary, United Bristol Healthcare NHS Trust, Bristol BS1 3NU, UK
2Avon Orthopaedics Centre, Southmead Hospital, North Bristol NHS Trust, Bristol BS16 1JE, UK
3Department of Orthopaedics, Weston General Hospital, Weston-Super-Mare BS23 4TQ, North Somerset, UK

Received 3 February 2006; Accepted 12 July 2006

Copyright © 2006 Verity A. Currall and John H. Dixon. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. G Silverman, “Multiple osteogenic sarcoma,” Archives of Pathology, vol. 21, pp. 88–95, 1936. View at Google Scholar
  2. R H Daffner, S L Kennedy, K R Fox, J J Crowley, D D Sauser, and L A Cooperstein, “Synchronous multicentric osteosarcoma: the case for metastases,” Skeletal Radiology, vol. 26, no. 10, pp. 569–578, 1997. View at Publisher · View at Google Scholar
  3. H C Amstutz, “Multiple osteogenic sarcomata - metastatic or multicentric? Report of two cases and review of literature,” Cancer, vol. 24, no. 5, pp. 923–931, 1969. View at Publisher · View at Google Scholar
  4. D M Parham, C B Pratt, L S Parvey, B L Webber, and J Champion, “Childhood multifocal osteosarcoma. Clinicopathologic and radiologic correlates,” Cancer, vol. 55, no. 11, pp. 2653–2658, 1985. View at Publisher · View at Google Scholar
  5. R J McKenna, C P Schwinn, K Y Soong, and N L Higinbotham, “Sarcomata of the osteogenic series (osteosarcoma, fibrosarcoma, chondrosarcoma, parosteal osteogenic sarcoma, and sarcomata arising in abnormal bone): an analysis of 552 cases,” The Journal of Bone and Joint Surgery. American Volume, vol. 48, pp. 1–26, 1966. View at Google Scholar
  6. D C Dahlin and M B Coventry, “Osteogenic sarcoma. A study of six hundred cases,” The Journal of Bone and Joint Surgery. American Volume, vol. 49, no. 1, pp. 101–110, 1967. View at Google Scholar
  7. R D Jones, R Reid, G Balakrishnan, and A Barrett, “Multifocal synchronous osteosarcoma: the Scottish Bone Tumour Registry experience,” Medical and Pediatric Oncology, vol. 21, no. 2, pp. 111–116, 1993. View at Publisher · View at Google Scholar
  8. R H Jr Fitzgerald, D C Dahlin, and F H Sim, “Multiple metachronous osteogenic sarcoma. Report of twelve cases with two long-term survivors,” Journal of Bone and Joint Surgery. American Volume, vol. 55, no. 3, pp. 595–605, 1973. View at Google Scholar
  9. C HG Price, “Multifocal osteogenic sarcoma,” The Journal of Bone and Joint Surgery. British Volume, vol. 39, pp. 524–533, 1957. View at Google Scholar
  10. A Iavarone, K K Matthay, T M Steinkirchner, and M A Israel, “Germ-line and somatic p53 gene mutations in multifocal osteogenic sarcoma,” Proceedings of the National Academy of Sciences of the United States of America, vol. 89, no. 9, pp. 4207–4209, 1992. View at Publisher · View at Google Scholar
  11. P Potepan, R Luksch, G Sozzi et al., “Multifocal osteosarcoma as second tumor after childhood retinoblastoma,” Skeletal Radiology, vol. 28, no. 7, pp. 415–421, 1999. View at Publisher · View at Google Scholar
  12. K D Hopper, R P Jr Moser, D B Haseman, D E Sweet, J E Madewell, and M J Kransdorf, “Osteosarcomatosis,” Radiology, vol. 175, no. 1, pp. 233–239, 1990. View at Google Scholar
  13. W F Enneking and A Kagan, ““Skip” metastases in osteosarcoma,” Cancer, vol. 36, no. 6, pp. 2192–2205, 1975. View at Google Scholar
  14. O V Batson, “The vertebral vein system,” American Journal of Roentgenology, vol. 78, pp. 195–212, 1957. View at Google Scholar
  15. M Hatori, H Ohtani, N Yamada, M Uzuki, and S Kokubun, “Synchronous multifocal osteosarcoma with lymphatic spread in the lung: an autopsy case report,” Japanese Journal of Clinical Oncology, vol. 31, no. 11, pp. 562–566, 2001. View at Publisher · View at Google Scholar
  16. G Bacci, A Longhi, S Ferrari et al., “Neoadjuvant chemotherapy (NC) for synchronous multifocal osteosarcoma (SMO),” in Proceedings of 37th Annual Meeting of the American Society of Clinical Oncology, San Francisco, Calif, May 2001. View at Google Scholar
  17. J P Mahoney, S S Spanier, and J L Morris, “Multifocal osteosarcoma. A case report with review of the literature,” Cancer, vol. 44, no. 5, pp. 1897–1907, 1979. View at Publisher · View at Google Scholar
  18. G Bacci, P Picci, S Ferrari et al., “Synchronous multifocal osteosarcoma: results in twelve patients treated with neoadjuvant chemotherapy and simultaneous resection of all involved bones,” Annals of Oncology, vol. 7, no. 8, pp. 864–866, 1996. View at Google Scholar