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Sarcoma
Volume 2007, Article ID 90169, 4 pages
http://dx.doi.org/10.1155/2007/90169
Case Report

Hepatic Angiosarcoma Presenting as an Acute Intraabdominal Hemorrhage Treated with Transarterial Chemoembolization

1Division of Vascular and Interventional Radiology, Department of Radiology, St. Joseph’s Hospital and Medical Center, Tampa, FL 33607, USA
2Department of Radiology, University College London Hospitals NHS Foundation Trust, London NW1 2BU, UK

Received 9 March 2007; Accepted 25 October 2007

Academic Editor: Alessandro Gronchi

Copyright © 2007 Glenn William Stambo and Michael J. Guiney. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Primary malignant neoplasms of the liver are some of the most uncommon malignancies in many parts of the world. They include hepatocellular carcinoma and stromal tumors such as hepatic angiosarcoma. It is a lethal tumor with life expectancy of less than six months. Once discovered, it is often too late for surgical intervention. Like other vascular tumors of the liver and spleen, intraperitoneal hemorrhage is a well-documented finding of angiosarcoma which can be lethal if not diagnosed and treated immediately. As in our case, intraperitoneal hemorrhage from primary tumor rupture was the only clinical presentation of this neoplasm. Approximately 15% of patients present with acute hemoperitoneum from either tumor rupture or peritoneal metastasis. Although several therapeutic options are available, we describe apalliative therapy for hepatic angiosarcoma utilizing transcatheter arterial chemoembolization (TACE) techniques incorporating the newer embolization agent Embospheres to locally target and treat this aggressive tumor.