Frequent EGFR Positivity and Overexpression in High-Grade Areas of Human MPNSTs

Table 1

Characteristics of the 52 patients with MPNST. NF1: Neurofibromatosis type 1; Spo: sporadic form of NF1 (no familial history), Fam: familial form of NF1; L: local stage; LA: locally advanced stage; Met: metastatic stage. A: alive. D: dead; +: positive staining; −: negative staining; n.e.: not evaluable staining.

Patient 𝑛^∘	NF1	Age/gender	Stage init	Localization	EGFR
R72	no	37/m	LA	Neck	+
R69	no	12/m	LA	Thigh	+
R92	no	11/w	LA	Brachial plexus	+
R78	no	28/w	L	Left arm	+
R94	no	52/m	L	Ethmoid	+
R86	no	33/f	L	Arm	+
R87	no	3/f	L	Tibial nerve	+
R77	no	71/f	L	Median nerve	+
R84	no	19/m	LA	Pelvis	+
R90	no	47/m	L	Right thigh	+
R74	no	16/f	L	Foot	+
R85	no	48/f	L	Forearm	+
R93	no	7/f	L	Mandible	+
R79	no	30/m	L	Wrist	+
R89	no	18/f	LA	Infratemporal fossa	+
R88	no	26/m	L	Left calf	0
R75	no	50/f	LA	Retroperitoneum	0
R76	no	23/m	L	Frontal region	0
B1027	no	15/m	LA	Retroperitoneum, pelvis	0
R73	no	7/m	LA	Neck	0
B1499	no	60/m	LA	Mediastinum	n.e.
R80	no	14/f	L	Left orbit	n.e.
B1044	no	7/m	L	Calf	n.e.
R95	no	20/m	Met	Hand	n.e.
R81	no	46/m	L	Forearm	n.e.
B1463	no	19/m	LA	Armpit	n.e.
R123	Fam	15/m	L	Median nerve	+
R118 B	Fam	11/f	LA	Brachial plexus	+
B1357	Spo	16/m	LA	Sciatic nerve	+
R107	Spo	33/m	L	Neck	+
R111	Spo	13/f	LA	Thigh	+
B1064	Spo	44/f	L	Thigh	+
R116	Spo	10/m	LA	Arm	+
R98	Spo	23/f	L	Calf	+
B2387	Spo	29/m	LA	Supraclavicular region	+
R122	Fam	19/f	LA	Groin	+
R104	Spo	25/m	L	Left calf	+
R97	Spo	17/m	LA	Left iliac	+
B1400	Fam	20/m	LA	Chest wall	+
R105	Spo	13/m	LA	Abdominal wall	+
R96	Spo	23/m	LA	Sciatic nerve buttock	+
R102	Spo	23/m	Méta	Retroperitoneum	+
R101	Spo	26/m	LA	Retroperitoneum	+
B1399	Spo	5/m	LA	Urinary bladder	+
R114	Spo	7/m	LA	Thigh	+
B1148	Fam	17/f	L	Thigh	+
bloc t	Spo	32/f	L	Thigh	+
B1793	Fam	32/f	L	Thigh	0
R127	Fam	11/f	LA	Left thigh (sciatic)	n.e.
R119	Fam	10/m	LA	Retroperitoneum	n.e.
R125	Fam	11/f	LA	Upper	n.e.
B1599	Spo	20/f	LA	Pelvis	n.e.