Immunohistochemical Estimates of Angiogenesis, Proliferative Activity, p53 Expression, and Multiple Drug Resistance Have No Prognostic Impact in Osteosarcoma: A Comparative Clinicopathological Investigation

Table 2

Histological radicality of surgery in relation to preoperative chemotherapy course^a. P value^b=.00002.

Type of histological radicality of surgical specimen:	Preoperative chemotherapy not given	Preoperative chemotherapy given	∑
Intralesional or marginal resection	5	4	9
Wide resection	19	30	49
Amputation	43	11	54
∑	67	45	112

^aFive patients did not receive surgical treatment, but were by own wish treated by either chemotherapy and/or radiation therapy alone/combined or refused any treatment.
^b𝜒²-test.