Outcomes of First-Line Chemotherapy in Patients with Advanced or Metastatic Leiomyosarcoma of Uterine and Non-Uterine Origin

Table 1

Patient characteristics, 𝑛=65.

	Non-Uterine LMS	%	Uterine LMS	%
	(𝑛=32)		(𝑛=33)
Gender
Male	13	41
Female	19	59	33	100
Median age at diagnosis	55.5	yrs	54.4	yrs
Range	30–74		33–74
Histology
Spindle cell	6	19	3	9
Epitheloid	0		2	6
Pleiomorph	7	22	6	18
Unknown	19	59	22	67
Primary disease localisation
Extremity	17	53	—
Non-extremity	15	47	—
Locally advanced disease
Without distant metastases	5	16	4	12
With distant metastases	6	19	12	36
Distant Metastases (M1)
One site, no liver	10	37	15	52
One site, liver	2	7	0	0
≥2 sites, no liver	8	30	9	31
≥2 sites, including liver	7	26	5	17
WHO PS before start chemotherapy
0	10	31	9	27
1	21	66	23	70
2	1	3	1	3