Collagenous Fibroma (Desmoplastic Fibroblastoma) with Vertebral Body Erosion

Table 1

Summary of the clinical, radiographic, and pathological characteristics of the tumors in the differential for collagenous fibroma.

Tumor type	Age, gender	Location	Imaging	Histology
Collagenous fibroma	Mainly males, between fifth and seventh decades of life	Extremities	Well-circumscribed	Hypocellular, with prominent collagenous background, entrapment of the soft tissue at the periphery.
Desmoid tumor (extra-abdominal)	Puberty-middle age, no gender predilection	Shoulder, chest wall, back, thigh, head and neck	Poorly defined	Variably cellular stroma containing compressed or distorted blood vessels
Gardner’s fibroma	Children, adolescents, no gender predilection	Paraspinal region, back, chest wall, flank, head and neck, extremities	Poorly defined	Hypocellular, entrapment of the soft tissue at the periphery. Not vascular.
Nuchal-type fibroma	Third through fifth decades of life, male predilection	Classically in the posterior neck	Poorly defined	Hypocellular, with haphazardly arranged collagen fibers, nerve twigs.