Research Article
Histopathological Diagnostic Discrepancies in Soft Tissue Tumours Referred to a Specialist Centre
Table 2
Minor discrepancies.
| (a) Diagnostic discrepancies |
| | Previous Diagnosis | Final Diagnosis | Number of cases |
| | Leiomyosarcoma | Pleomorphic sarcoma | 4 | | Spindle cell sarcoma, myofibroblastic differentiation | 2 | | Myofibrosarcoma | 1 | | Myxofibrosarcoma | 1 | | Leiomyosarcoma, pleomorphic | Spindle cell sarcoma | 1 | | Rhabdomyosarcoma | Pleomorphic sarcoma, myogenic differentiation | 1 | | Pleomorphic sarcoma, smooth muscle differentiation | 1 | | Liposarcoma, pleomorphic | Myxofibrosarcoma | 2 | | Myxoid liposarcoma | 1 | | Liposarcoma, dedifferentiated | Spindle cell rhabdomyosarcoma | 1 | | Synovial sarcoma | SFT, malignant | 1 | | Extraskeletal osteosarcoma | Pleomorphic sarcoma | 1 | | Chondrosarcoma | Extraskeletal osteosarcoma with focal chondrosarcomatous areas | 1 | | Mesenchymal chondrosarcoma | Pleomorphic sarcoma | 1 | | Epithelioid haemangioendothelioma | Epithelioid haemangioma | 1 | | Sarcoma NOS | SFT | 1 | | Spindle cell sarcoma | Leiomyosarcoma | 1 | | Pleomorphic sarcoma | Myxoinflammatory fibroblastic sarcoma | 1 | | Spindle cell proliferation | Fibromatosis | 2 | | Fibrosarcoma, grade 1 | 1 | | IMT | 1 | | Spindle cell proliferation, atypical | Leiomyosarcoma, grade 1 | 1 | | Spindle cell sarcoma NOS | 1 |
|
|
| (b) Classification discrepancies |
| | Previous Diagnosis | Final Diagnosis | Number of cases |
| | Smooth muscle tumour, low malignant potential | Leiomyosarcoma, grade 2 | 1 | | Leiomyosarcoma | Cutaneous leiomyosarcoma | 1 | | Leiomyosarcoma, cutaneous | Leiomyosarcoma (non-cutaneous) | 1 | | Pleomorphic leiomyosarcoma | Leiomyosarcoma | 1 | | Uterine fibroid | Smooth muscle tumour of uncertain malignant potential | 1 | | Leiomyosarcoma, grade 1 | Atypical leiomyoma | 1 | | Smooth muscle tumour of uncertain malignant potential | 1 | | Rhabdomyosarcoma | Pleomorphic sarcoma with myogenic differentiation | 1 | | Pleomorphic rhabdomyosarcoma | Embryonal rhabdomyosarcoma, anaplastic variant | 1 | | Alveolar rhabdomyosarcoma | 1 | | Pleomorphic sarcoma | 1 | | Liposarcoma | Myxoid-round cell liposarcoma, grade 2 | 1 | | PNET | Primitive malignant tumour with rhabdomyosarcomatous and neural differentiation | 1 | | Endometrial stromal sarcoma, high grade | Endometrial stromal sarcoma, low grade | 1 | | Pleomorphic sarcoma, rhabdomyosarcomatous differentiation | Pleomorphic sarcoma, myofibroblastic differentiation | 1 | | ?Sarcoma ?carcinoma | Pleomorphic sarcoma | 1 | | Synovial sarcoma | 1 | | Pleomorphic sarcoma | Myxofibrosarcoma | 1 |
|
|
| (c) Grading discrepancies |
| | Previous Grade | Final Grade | Number of cases |
| | Leiomyosarcoma, grade 2 | Grade 3 | 2 | | Pleomorphic liposarcoma, grade 3 | Grade 2 | 3 | | Pleomorphic sarcoma, grade 3 | Grade 2 | 2 | | GIST, high risk | Intermediate risk | 1 |
|
|
