Clinical Study

Clinical Benefit of Second-Line Palliative Chemotherapy in Advanced Soft-Tissue Sarcoma

Table 1

Clinical characteristics.

Patients379

SexMale : Female176 : 203

Age at 2nd-Line chemo (years)Median (Range)50 (18–81)

HistologyLeiomyosarcoma134 (35.4%)
Synovial sarcoma52 (13.7%)
Liposarcoma39(10.3%)
Other:154 (40.6%)
 Malignant Fibrous Histiocytoma25
 Sarcoma (not otherwise specified) 30
 Fibrosarcoma 9
 Malignant Peripheral nerve sheath tumour 12
 Angiosarcoma 18
 Other 60

DiseaseAdvanced40 (10.6%)
Metastatic—single organ186 (49.1%)
Metastatic—multiple organs153 (40.4%)

Sites of metastasesLung231 (60.9%)
Liver73 (19.3%)
Bone23 (6.1%)