Molecular Characterization of Putative Chordoma Cell Lines
Gene expression analysis of chordoma tumors, putative chordoma cell lines, and normal tissues including intervertebral disk (IVD). Five chordoma-specific genes from among the 2351 probe sets used for cluster analysis are included; T: brachyury, KRT19: keratin19, Col2A1: collagen 2A1, CA3: carbonic anhydrase 3, and CD24. Genes with decreased relative expression are shown in green while those with increased relative expression are shown in red. Chordoma tumors (Chordoma and Chordoma-MK) and cell lines U-CH1, U-CH2, and K001 have similar expression patterns distinct from the other putative chordoma cell lines and other tissues.