Research Article

Preclinical Testing of Erlotinib in a Transgenic Alveolar Rhabdomyosarcoma Mouse Model

Figure 3

Histological and biochemical analysis of untreated and Erlotinib-treated tumors. Representative histology of (a) untreated and (b) Erlotinib-treated tumors. (c) Mitotic figures/10 high-power fields for untreated and Erlotinib-treated mice ( 𝑃 = 0 . 8 4 1 ). (d) Western blots showing the expression and phosphorylation of Egfr in primary tumor cell cultures from Erlotinib-treated mice.
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