Axial Skeletal Location Predicts Poor Outcome in Ewing's Sarcoma: A Single Institution Experience

Table 1

Patient Information. Table 1 depicts demographic data, pretreatment characteristics, and treatment characteristics for the axial EWS and appendicular EWS groups.

	Axial EWS (𝑛=34, 51%)	Appendicular EWS (𝑛=33, 49%)	Total (𝑛=67)	𝑃 value
Pretreatment Factors
Median Age	25.1	28.7	26.9	0.23
No. male	21 (62%)	20 (61%)	41 (61%)	0.30
No. female	13 (38%)	13 (39%)	26 (39%)	—
No. bone	31 (91%)	26 (79%)	57 (85%)	0.19
No. soft tissue (ST)	3 (9%)	7 (21%)	10 (15%)	—
No. with metastases at diagnosis	10 (29%)	5 (15%)	15 (22%)	0.33
No. bone lesions over 8 cm	21 (62%)	17 (52%)	38 (57%)	0.9
No. bone lesions under 8 cm	10 (29%)	9 (27%)	19 (28%)	—
No. ST lesions over 5 cm	1 (3%)	4 (12%)	5 (7%)	1.0
No. ST lesions under 5 cm	2 (6%)	3 (9%)	5 (7%)	—
Treatment Factors
No. receiving definitive treatment	25 (74%)	29 (88%)	54 (81%)	0.22
No. receiving definitive surgery	16 (47%)	28 (85%)	44 (66%)	0.0018
No. receiving definitive XRT	9 (26%)	1 (3%)	10 (15%)	0.013
No. not receiving surgery or XRT	9 (26%)	4 (12%)	13 (19%)	0.22
No. receiving adjuvant XRT	8 (24%)	2 (6%)	10 (15%)	0.045
Outcome Parameters
No. positive margins	6 (18%)	3 (9%)	9 (13%)	0.0031
No. local recurrences	5 (15%)	0 (0%)	5 (7%)	0.053
No. ANED	10 (29%)	22 (67%)	32 (48%)
No. AWED	2 (6%)	1 (3%)	3 (4%)
No. DOD	22 (65%)	10 (30%)	32 (48%)
% 5-year OS	29%	66%		0.002