Clinical Study

Prognostic Factors and Metastatic Patterns in Primary Myxoid/Round-Cell Liposarcoma

Table 1

Risk factors for local recurrence at 5 years following tumour resection with hazards ratio estimates, 95% confidence limits and 𝑃 values.

Factor5 years risk of LRHR95% CI 𝑃 value

Overall13%

Depth:
 Superficial9%1.460.42–5.000.55
 Deep14%1

Size:
 Up to 5 cm50%2.2850.63–8.270.208
 >5 cm to <10 cm7%0.6810.24–1.960.476
 >10 cm14%1

Site:
 Lower extremity12%0.2690.06–1.180.081
 Upper extremity40%1
 Trunk20%0.6050.60–6.760.683

Histology:
 Pure myxoid9%1
 0–5% round cell4%0.4720.055–4.040.493
 >5% round cell26%3.3211.12–9.820.03

Margin:
 Intralesional34%2.4450.85–7.060.098
 Marginal6%0.3950.13–1.210.103
 Wide15%1

Surgery:
 Amputation10%0.6250.083–4.690.648
 Limb salvage13%1

Postoperative radiotherapy11%1
No radiotherapy17%1.130.429–2.9770.80