Prognostic Factors and Metastatic Patterns in Primary Myxoid/Round-Cell Liposarcoma

Table 3

Factors affecting disease specific survival, showing hazards ratio estimates, 95% confidence limits and 𝑃 values.

Factor	5 years disease specific survival	HR	95% CI	𝑃 value
Overall	75%
Age under 50	81%	0.543	0.36–1.12	0.139
Age over 50	66%	1
Depth:
Superficial	87%	1
Deep	71%	1.69	0.72–3.99	0.232
Size:
Up to 5 cm	73%	0.647	0.15–2.71	0.552
> 5 cm to <10 cm	78%	0.607	0.31–1.18	0.143
>10 cm	72%	1
Site:
Lower extremity	76%	0.793	0.19–3.29	0.749
Upper extremity	60%	1
Trunk	50%	1.142	0.10–12.89	0.914
Histology:
Pure myxoid	91%	1
0–5% round cell	88%	2.785	0.80–9.69	0.107
>5% round cell	58%	6.897	2.53–18.82	0.0002
Margin:
Intralesional	70%	1.493	0.65–3.46	0.34
Marginal	78%	0.721	0.38–1.38	0.32
Wide	71%	1
Surgery:
Amputation	51%	3.062	1.47–6.37	0.0027
Limb salvage	77%	1
Postoperative radiotherapy	76%	1
No radiotherapy	74%	0.975	0.50–1.89	0.975