Research Article
Impairment of Methotrexate Transport Is Common in Osteosarcoma Tumor Samples
Table 1
Displacement of methotrexate and trimexate by PT430 grouped by sample type.
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aThe MTX : TMTX differential displacement ratio represents the percentage of PT430 displaced by methotrexate in relation to the percentage of PT430 displaced by trimetrexate. For example, a sample with methotrexate displacement of 25% and trimetrexate displacement of 50% would have an MTX : TMTX differential displacement ratio of 0.50. |