Sequential Dose-Dense Doxorubicin and Ifosfamide in Advanced Soft-Tissue Sarcoma Patients in an Out-Patient-Basis Schedule

Table 1

Patient characteristics.

	META^a	LOCA^b	Total
	N (%)	N (%)	N (%)
Total	13 (65)	7 (35)	20 (100)
Sex
Male	7 (35)	5 (25)	12 (60)
Female	6 (30)	2 (10)	8 (40)
Age (years)
Median	47	28	39
Range	26–60	25–45	25–60
Performance status
0	4	4	8
1	6	3	9
2	3	0	3
Histological subtype
Synovial	1	4	5
Leiomyo	5	0	5
Unclassified	2	2	4
Malignant fibrohistiocytoma	2	0	2
Myxoid	1	1	2
Other^c	1	1	2
Primary site
Lower limbs	3	5	8
Retroperitoneal	5	0	5
Upper limbs	2	2	4
Other^d	3	0	3
Size of primary tumor (cm)
Median	12.4	11.7	12
Range	2–18	6.1–15	2–18
Metastatic site
Lung	11	NA	11
Lymph node	5	NA	5
Liver	4	NA	4
Bone	4	NA	4
Other^e	4	NA	4
Number of metastatic sites
1	5	NA	5
2	3	NA	3
≥3	5	NA	5

^aMETA: metastatic disease.
^bLOCA: locally advanced disease.
^cEpithelioid, malignant peripheral nerve sheath tumor.
^dLung, uterus, scalp.
^eSpleen, adrenal gland, pleura.
NA: not applicable.