Low Prevalence of TP53 Mutations and MDM2 Amplifications in Pediatric Rhabdomyosarcoma

Table 4

Mean age of first tumor onset according to the combined MDM2 SNP309 or p53 codon 72 genotype.

Number of at risk loci	Corresponding genotypes	Number of patients	Mean age ± STDEV (years)
0	T/T + Pro/Pro	1	9.0 ± 0.0
1	(T/G or G/G + Pro/Pro) or (T/T + Arg/Arg or Arg/Pro)	18	6.2 ± 5.2
2	T/G or G/G + Arg/Arg or Arg/Pro	21	7.1 ± 4.8