Prognostic Impacts of Hypoxic Markers in Soft Tissue Sarcoma

Table 2

Correlation between expression of hypoxic markers and clinicopathological variables.

	GLUT-1	HIF-1α	HIF-2α	CAIX
GLUT-1		𝑟=0.08	𝑟=0.11	𝑟=0.18
		𝑃=0.29	𝑃=0.12	𝑃=0.013
HIF-1α	𝑟=0.08		𝐫=𝟎.𝟐𝟕	𝑅=0.18
	𝑃=0.29		𝐏<𝟎.𝟎𝟎𝟏	𝑃=0.013
HIF-2α	𝑟=0.11	𝐫=𝟎.𝟐𝟕		𝑟=0.17
	𝑃=0.12	𝐏<𝟎.𝟎𝟎𝟏		𝑃=0.017
CAIX	𝑟=0.18	𝑟=0.18	𝑟=0.17
	𝑃=0.013	𝑃=0.013	𝑃=0.017
Age	𝑟=0.12	𝑟=0.15	𝑟=−0.04	𝑟=−0.02
	𝑃=0.11	𝑃=0.93	𝑃=0.58	𝑃=0.74
Gender	𝑟=0.13	𝑟=−0.001	𝑟=0.07	𝑟=0.10
	𝑃=0.07	𝑃=0.97	𝑃=0.30	𝑃=0.17
Patient nationality	𝑟=−0.03	𝑟=−0.15	𝑟=0.17	𝑟=0.001
	𝑃=0.67	𝑃=0.03	𝑃=0.02	𝑃=0.97
Histological entity	𝑟=0.08	𝑟=−0.05	𝑟=−0.06	𝑟=−0.03
	𝑃=0.30	𝑃=0.49	𝑃=0.43	𝑃=0.66
Tumor localization	𝑟=0.09	𝑟=−0.02	𝑟=0.03	𝑟=0.19
	𝑃=0.23	𝑃=0.74	𝑃=0.69	𝑃=0.006
Tumor size	𝑟=0.04	𝑟=−0.004	𝑟=0.01	𝑟=−0.01
	𝑃=0.59	𝑃=0.95	𝑃=0.85	𝑃=0.92
Malignancy grade	𝐫=𝟎.𝟑𝟓	𝑟=−0.01	𝐫=𝟎.𝟐𝟑	𝑟=0.13
	𝐏<𝟎.𝟎𝟎𝟏	𝑃=0.85	𝐏=𝟎.𝟎𝟎𝟏	𝑃=0.06
Tumor depth	𝑟=0.10	𝑟=0.07	𝑟=−0.05	𝑟=0.03
	𝑃=0.19	𝑃=0.33	𝑃=0.49	𝑃=0.71
Resection margins	𝑟=−0.10	𝑟=−0.13	𝑟=−0.13	𝑟=−0.05
	𝑃=0.18	𝑃=0.06	𝑃=0.07	𝑃=0.49

𝑟 = correlation coefficient.