Clinical Study

Prognostic Value of Microvessel Density in Tumor and Peritumoral Area as Evaluated by CD31 Protein Expression and Argyrophilic Nucleolar Organizer Region Count in Endothelial Cells in Uterine Leiomyosarcoma

Figure 4

MVD (as evaluated by CD31 expression) in LMS vessels ((b), (d), (f)) and peritumoral area ((a), (c), (e)). Immunohistochemistry technique, magnification ×200. There were no significant differences in the MVD between LMS and the PA. MVD in LMS at grade 1 phase (b) was higher than at grade 2 and grade 3 phases; however, in each tumor case, indices varied in the same manner as the MVD in the PA. A positive control for CD31 (capillary hemangioma, ×400) is shown in the left upper corner.
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