Prognostic Value of Microvessel Density in Tumor and Peritumoral Area as Evaluated by CD31 Protein Expression and Argyrophilic Nucleolar Organizer Region Count in Endothelial Cells in Uterine Leiomyosarcoma
Figure 4
MVD (as evaluated by CD31 expression) in LMS vessels ((b), (d), (f)) and peritumoral area ((a), (c), (e)). Immunohistochemistry technique, magnification ×200. There were no significant differences in the MVD between LMS and the PA. MVD in LMS at grade 1 phase (b) was higher than at grade 2 and grade 3 phases; however, in each tumor case, indices varied in the same manner as the MVD in the PA. A positive control for CD31 (capillary hemangioma, ×400) is shown in the left upper corner.