Research Article

Genes Regulated in Metastatic Osteosarcoma: Evaluation by Microarray Analysis in Four Human and Two Mouse Cell Line Systems

Table 1

Number of regulated (>2-fold; fdr < 0.01) probe sets in human and mouse OS cell line systems.

SystemTotal (%)aUp (%)bDown (%)b

Human
 SAOS/LM51351 (2.5)668 (49)683 (51)
 HUO9/M1321975 (3.6)1001 (51)974 (49)
 HOS/143B3652 (6.7)1690 (46)1962 (54)
 MG63/M8521 (1.0)292 (56)229 (44)
Mouse
 Dunn/LM81217 (2.7)494 (41)723 (59)
 K12/K7M23749 (8.3)1769 (47)1980 (53)

aPercent of the total number of probe sets represented by the human (54675) and mouse arrays (45101); bpercent of the total number of regulated probe sets.