Genes Regulated in Metastatic Osteosarcoma: Evaluation by Microarray Analysis in Four Human and Two Mouse Cell Line Systems

Table 2

Number of regulated (>2-fold; fdr < 0.01) probe sets enriched (fdr < 0.00001) in GO terms level 1.

	SAOS/LM5	HU09/M132	HOS/143B	MG63/M8	Dunn/LM8	K12/K7M2
Cellular component
Cell	884	1244	2519	362	780	2423
Membrane	486			206	475
Extracellular region	196	266	403	96	218	365
Extracellular matrix	78		143		88	134
Synapse			112
Molecular function
Binding	850	1219	2435	343	805	2391
Molecular transducer activity		189	302
Nucleic acid binding transcription factor activity		138	249
Receptor activity		206
Catalytic activity						1062
Biological process
Cellular process	716	1017	2028		638	1858
Biological regulation	517	793	1537	250	522	1378
Response to stimulus		589	1074		376	1010
Multicellular organismal process	400	562	1055	186	369	846
Developmental process	345	490	931	159	351	768
Signaling		399		139	227	567
Biological adhesion	110	145	260	53	70	193
Growth	43		78			85
Locomotion		107				148
Cellular component organization or biogenesis			642			558
Localization			643
Cell proliferation			133
Rhythmic process			57
Reproduction					83
Immune system process					92
Multiorganism process						129
Metabolic process						1132
Death						168