Should Aggressive Surgical Local Control Be Attempted in All Patients with Metastatic or Pelvic Ewing's Sarcoma?

Table 5

Data for patients with local recurrence.

Patient	Location	Local control	Time till recurrence (years)^†	Treatment for recurrence	Outcome; (at latest followup)
1	2nd Metatarsal	Surgery	2.3	Ifosfamide, Carboplatinum, Etoposide	Alive with evidence of disease
2	Chest wall	Surgery	6	Resection	Died of disease
3	Deltoid (ST)	Radiation	1.2	Forequarter amputation	Died of disease
4	Femur	Surgery	3.1	Reinduction chemotherapy/Distal femur resection	Died of disease
5	Chest wall	Surgery/(initial surgery: incomplete resection at OSH)/then chest wall resection for increasing size while on chemotherapy	0.7	None	Died of disease
6	Chest wall	Surgery	1.2	Resection/Cytoxan/Topotecan	Died of disease
7	Pelvic/ovary (ST)	Surgery	0.1	None	Died of disease
8	Thigh	Surgery	0.2	Resection/Vincristine/Doxorubicin/ Cyclophosphamide	Died of disease
9	Clavicle	Surgery	2.4	Resection/Ifosfamide/Etoposide/ Cytoxan/Topotecan	Alive with evidence of disease
10	Femur	Surgery	0.9	None	Died of disease
11	Popliteal (ST)	Surgery	2.8	Above knee amputation	Alive with evidence of disease
12	Pelvis	Radiation/surgery	1	None	Died of disease
13	Femur	Radiation	2.2	Proximal femur resection	Alive without evidence of disease
14	Pelvis	Radiation	1.4	Hemipelvectomy/Cytoxan/Topotecan/XRT	Died of disease
15	Humerus	Unknown	2.1	Shoulder disarticulation	Alive with evidence of disease

^†: Time to recurrence calculated from date of diagnosis.
ST: soft tissue Ewing’s.