Sustained Low-Dose Treatment with the Histone Deacetylase Inhibitor LBH589 Induces Terminal Differentiation of Osteosarcoma Cells
Figure 3
Low-dose LBH589 treatment induces cell cycle arrest and senescence. Heatmap representation of differentially expressed genes enriched in functional groups associated with (a) cell cycle regulation, (b) senescence-associated secretory phenotype, and (c) apoptosis. Each column represents a distinct sample.
