| | Variable | Overall
() | No RT
() | Adjuvant only
() | value |
| | Patient characteristics | | | | | | Age, yrs. (IQR) | 57 (45, 70) | 57 (46, 70) | 54 (44, 68) | 0.006 | | Female | 676 (47.7%) | 484 (47.7%) | 192 (47.5%) | 0.991 | | Race | | | | 0.875 | | White | 1,171 (84.2%) | 837 (84%) | 334 (84.6%) | | | Black | 160 (11.5%) | 117 (11.7%) | 43 (10.9%) | | | Other | 60 (4.3%) | 42 (4.2%) | 18 (4.6%) | | | Charlson Comorbidity Score | | | | 0.791 | | 0—none | 836 (88.2%) | 600 (88%) | 236 (88.7%) | | | 1—one point | 97 (10.2%) | 72 (10.6%) | 25 (9.4%) | | | 2—two or more points | 15 (1.6%) | 10 (1.5%) | 5 (1.9%) | | | Education above median | 820 (61.2%) | 576 (60.4%) | 244 (63.2%) | 0.367 | | Income above median | 922 (68.8%) | 647 (67.8%) | 275 (71.2%) | 0.246 | | Distance to cancer center (IQR) | 14.2 (5.8, 39.5) | 15.5 (6.2, 44.5) | 11 (5.3, 26.8) | 0.867 | | Treatment facility | | | | 0.021 | | Community Cancer Program | 74 (5.3%) | 47 (4.8%) | 27 (6.8%) | | | Comprehensive Community Cancer Program | 534 (38.5%) | 364 (36.8%) | 170 (42.6%) | | | Academic/Research Program | 780 (56.2%) | 578 (58.4%) | 202 (50.6%) | | | Uninsured | 43 (3.1%) | 30 (3.1%) | 13 (3.3%) | 0.956 |
| | Tumor characteristics | | | | | | Limb location | | | | 0.856 | | Upper limb and shoulder | 212 (15%) | 150 (14.8%) | 62 (15.3%) | | | Lower limb and hip | 1,206 (85%) | 864 (85.2%) | 342 (84.7%) | | | Tumor size (mm) | 130 (70, 200) | 133 (70, 200) | 121 (71.5, 185) | 0.009 | | Tumor size | | | | 0.002 | | 5 cm | 197 (15.7%) | 149 (16.9%) | 48 (12.8%) | | | 5–9.9 cm | 262 (20.9%) | 173 (19.7%) | 89 (23.7%) | | | 10.0–19.9 cm | 457 (36.4%) | 300 (34.1%) | 157 (41.9%) | | | >20.0 cm | 339 (27%) | 258 (29.3%) | 81 (21.6%) | | | Histology | | | | 0.999 | | Liposarcoma | 1,418 (100%) | 1,014 (100%) | 404 (100%) | |
| | Treatment specifics | | | | | | Surgery type | | | | 0.439 | | Local excision | 461 (32.5%) | 337 (33.2%) | 124 (30.7%) | | | Radical resection | 938 (66.1%) | 661 (65.2%) | 277 (68.6%) | | | Limb amputation | 18 (1.3%) | 15 (1.5%) | 3 (0.7%) | 0.31 | | Major amputation | 1 (0.1%) | 1 (0.1%) | 0 (0%) | | | Days to definitive surgery (IQR) | 0 (0, 27) | 0 (0, 24) | 9 (0, 34.5) | 0.393 |
| | Selection of adjuvant RT by surgical margin | | | | | | Surgical margins | | | | 0.014 | | Negative | 946 (74.9%) | 684 (76.7%) | 262 (70.6%) | | | Positive margin, microscopic | 182 (14.4%) | 112 (12.6%) | 70 (18.9%) | | | Positive margin, macroscopic | 135 (10.7%) | 96 (10.8%) | 39 (10.5%) | | | 30-day readmission | 25 (2.7%) | 21 (3.2%) | 4 (1.6%) | 0.257 | | Hospital LOS (IQR) | 1 (0, 3) | 1 (0, 3) | 1 (0, 3) | 0.452 |
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