Studies identifying stem cells in RMS.
|Marker/substrate||Source||Stem cell gene||Functional characterization||Reference|
|CD133||Orthotopic xenograft model||OCT4, NANOG, c-MYC, PAX3, and SOX2||Correlating with poor overall survival||Walter et al., 2011 |
|PAX-FKHR||Bone marrow of C57BL/6 mice||Myf5, MEF2, MyoD, and myogenin||Determining the molecular, myogenic, and histologic phenotype of ARMS||Ren et al., 2008 |
|V-ATPase||RD cell line||NANOG and OCT3/4||Driving mechanisms of a reduced sensitivity to anticancer drugs and activities related to invasion and metastasis||Salerno et al., 2014 |
|Surv.m-CRAs||KYM-1 cell line (FGFR3-positive)||FGFR3||Therapeutic effectiveness against all cell populations and increased effectiveness against CSCs||Tanoue et al., 2014 |