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| Time on treatment (months) | Best response (RECIST) | Maximal change of tumor (%) | Treatment after GDB | Pathology from surgery | Outcome |
|
63 y male with recurrent UPS of thigh | 1.4 | PR | −39 | Resection of local recurrence | Treatment effect but viable tumor | NED at 3.1 y |
55 y female with recurrent UPS of thigh | 2.1 | SD | 0 | Limb perfusion and then surgery | 30–40% necrosis and fibrosis | NED at 3.5 y |
44 y female with angiosarcoma of vagina | 3.0 | PR | −63 | Observation since biopsy showed no tumor | No tumor detected | NED at 1.3 y |
55 y male with metastatic LMS | 3.5 | PR | −31 | Resection of lung metastases | Necrosis and histiocytic infiltration (70%) | DOD at 1.4 y |
50 y female with large pelvic (nonuterine) LMS | 3.7 | SD | −11 | Evaluated for surgery but unresectable | N/A | AWD at 2.5 y |
39 y male with metastatic LMS | 4.2 | SD | −15 | Radio-frequency ablation of liver metastases | N/A | DOD at 2.4 y |
69 y female with metastatic uterine LMS | 4.5 | SD | −24 | Resection of pelvic metastases | Predominantly viable | AWD at 2.2 y |
40 y male with metastatic UPS | 4.6 | PR | −32 | Resection of lung metastases | Viable tumor | DOD at 1 y |
52 y male with metastatic angiosarcoma | 5.6 | PR | −31 | Resection of lung metastases | Viable but microscopic tumor | AWD at 11 m |
56 y male with metastatic pleomorphic liposarcoma | 7.0 | SD | −30 | Resection of solitary bone metastasis | >99% necrosis, rare viable cells | NED at 3.1 y |
52 y male with metastatic LMS | 8.4 | PR | −32 | Resection of lung metastases | 95% treatment effect | AWD at 2.2 y |
72 y female with metastatic UPS | 8.9 | PR | −55 | Observation and then further chemotherapy | N/A | AWD at 2.6 y |
57 y female with metastatic uterine LMS | 11.4 | PR | −43 | Resection of lung metastases | 30% treatment effect | DOD at 1.9 y |
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