Long-Term Clinical Responses of Neoadjuvant Dendritic Cell Infusions and Radiation in Soft Tissue Sarcoma

Table 3

Histological type, immune responses to tumor cell lysates, and proliferation and immune response to survivin, percentage of tumor necrosis, and survival in months data of 18 patients recieving neoadjuvant radiation and dendritic cell vaccine treatment.

ID	Histology	Age	Gender	Location	Survival in months	Tumor necrosis in %	Progression to lung metastases in days	Immune response to TCL proliferation	Immune response to TCL (IFN/Elispot)	Immune response to survivin
1	Myxoid liposarcoma	41	M	Groin	103	NA		Positive	Positive	Negative
2	Synovial sarcoma	53	M	Right shoulder	96	NA	951	Negative	Positive	NA
3	Dedifferentiated liposarcoma	46	F	Right thigh	103	70%		Negative	Negative	Positive
4	Spindle/; pleomorphic	69	F	Left knee	59	98%		NA	NA	NA
5	Undifferentiated pleomorphic sarcoma	64	F	Left pelvis	80	80%		Negative	Negative	Negative
6	Sarcoma with myxoid and chondroid features	73	F	Lumbar spine	53	53%		Negative	Negative	Negative
7	Pleomorphic sarcoma	79	M	Left arm	76	25%		Positive	Negative	Negative
8	Undifferentiated pleomorphic sarcoma	71	M	Left thigh	14	70%	142	Negative	Negative	Positive
9	Myxoid liposarcoma	55	M		52	NA		Positive	Positive	Negative
10	Fibrosarcoma	73	M	Back	85	NA		Positive	Positive	Negative
11	Spindle cell sarcoma	81	M	Right flank	77	10%		Negative	Negative	NA
12	Synovial sarcoma	25	M	Left thigh	28	NA	146	Positive	Negative	NA
13	Fibrosarcoma	52	M	Right thigh	30	20%	132	Positive	Negative	NA
14	Undifferentiated pleomorphic sarcoma	58	M	Left thigh	7	90%	48	NA	NA	NA
15	Synovial sarcoma	34	M	Left knee	39	70%	947	NA	NA	NA
16	Undifferentiated pleomorphic sarcoma	60	M	Right leg	87	40%		Negative	Negative	NA
17	Spindle cell sarcoma	81	M	Right flank	36	95%		NA	NA	NA
18	Undifferentiated pleomorphic sarcoma	50	M	Right paraspinal	18	5%	102	Positive	Negative	NA