| (a) |
| | Author, year | Study participation:
Dates of researched period stated
Clearly defined patient sample, assembled at a common point in course of the disease | Study attrition:
Sufficiently long and complete
follow-up (≥2 years and ≥80%)
Explaining reasons for patients being lost to follow-up | Confounding measurement:
Defined and comparable treatment for patients |
| | Andreou et al., 2011 [15] | 1 | 1 | 1, types of surgery mentioned | | Angelini et al., 2012 [16] | 1 | 1 | 1, types of surgery mentioned | | Briccoli et al., 2002 [17] | 1 | 0 | 1, types of surgery mentioned | | Cho et al., 2011 [18] | 1 | 1 | 1, types of surgery mentioned | | de Camargo et al., 2010 [19] | 1 | 1 | 1, types of surgery mentioned | | Donati et al., 2010 [20] | 1 | 1 | 1, types of surgery mentioned | | Donati et al., 2005 [21] | 1 | 1 | 1, types of surgery mentioned | | Gitelis et al., 1981 [22] | 1 | 1 | 1, types of surgery mentioned | | Mavrogenis et al., 2013 [23] | 1 | 1 | 1, types of surgery mentioned | | Mitchell et al., 2000 [10] | 1 | 0 | 1, types of surgery mentioned | | Ozaki et al., 1996 [24] | 1 | 1 | 1, types of surgery mentioned | | Staals et al., 2006 [25] | 1 | 0 | 1, types of surgery mentioned | | van Maldegem et al., 2014 [26] | 1 | 0 | 1, types of surgery mentioned |
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|
| (b) |
| | Author, year | Analysis:
Valid statistical analysis is done
Multivariable analysis is done | Population:
(no overlap) | Disclosure |
| | Andreou et al., 2011 [15] | 1 | 1 | 1 | | Angelini et al., 2012 [16] | 1 | 0 | 1 | | Briccoli et al., 2002 [17] | 0 | 0 | 0 | | Cho et al., 2011 [18] | 0 | 1 | 1 | | de Camargo et al., 2010 [19] | 0 | 1 | 1 | | Donati et al., 2010 [20] | 0 | 0 | 1 | | Donati et al., 2005 [21] | 1, but not on central survival | 0 | 1 | | Gitelis et al., 1981 [22] | 0 | 0 | 0 | | Mavrogenis et al., 2013 [23] | 1 | 0 | 1 | | Mitchell et al., 2000 [10] | 0 | 1 | 1 | | Ozaki et al., 1996 [24] | 0 | 1 | 0 | | Staals et al., 2006 [25] | 0 | 0 | 0 | | van Maldegem et al., 2014 [26] | 0 | 0 | 1 |
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|
| (c) |
| | Author, year | Prognostic factor measurement:
Clear definition and valid assessment of prognostic factors | Outcome measurement:
Well defined outcome parameters (survival: overall, metastatic-free, event-free) |
| | Andreou et al., 2011 [15] | 1 | 1 | | Angelini et al., 2012 [16] | 1 | 1 | | Briccoli et al., 2002 [17] | 0 | 0 | | Cho et al., 2011 [18] | 1 | 1 | | de Camargo et al., 2010 [19] | 1 | 1 | | Donati et al., 2010 [20] | 1 | 0 | | Donati et al., 2005 [21] | 1 | 0 | | Gitelis et al., 1981 [22] | 1 | 1 | | Mavrogenis et al., 2013 [23] | 1 | 1 | | Mitchell et al., 2000 [10] | 1 | 0 | | Ozaki et al., 1996 [24] | 1 | 1 | | Staals et al., 2006 [25] | 1 | 1 | | van Maldegem et al., 2014 [26] | 1 | 1 |
|
|
| (d) |
| | Author, year | FU >1 year | Level of evidence I–IV |
| | Andreou et al., 2011 [15] | 1 | 4, prognostic | | Angelini et al., 2012 [16] | 1 | 4, prognostic | | Briccoli et al., 2002 [17] | 0 | 4, prognostic | | Cho et al., 2011 [18] | 1 | 3, therapeutic | | de Camargo et al., 2010 [19] | 1 | 4, prognostic | | Donati et al., 2010 [20] | 1 | 2, prognostic | | Donati et al., 2005 [21] | 1 | 4, prognostic | | Gitelis et al., 1981 [22] | 1 | 4, prognostic | | Mavrogenis et al., 2013 [23] | 1 | 4, prognostic | | Mitchell et al., 2000 [10] | 1 | 4, prognostic | | Ozaki et al., 1996 [24] | 1 | 4, prognostic | | Staals et al., 2006 [25] | 0 | 4, prognostic | | van Maldegem et al., 2014 [26] | 1 | 4, prognostic |
|
|
| (e) |
| | Author, year | Confounding measurement
Defined and comparable treatment for patients | Baseline |
| | Andreou et al., 2011 [15] | 1, types of surgery mentioned | 0 | | Angelini et al., 2012 [16] | 1, types of surgery mentioned | 0 | | Briccoli et al., 2002 [17] | 1, types of surgery mentioned | 1 | | Cho et al., 2011 [18] | 1, types of surgery mentioned | 0 | | de Camargo et al., 2010 [19] | 1, types of surgery mentioned | 0 | | Donati et al., 2010 [20] | 1, types of surgery mentioned | 1 | | Donati et al., 2005 [21] | 1, types of surgery mentioned | 0 | | Gitelis et al., 1981 [22] | 1, types of surgery mentioned | 1 | | Mavrogenis et al., 2013 [23] | 1, types of surgery mentioned | 0 | | Mitchell et al., 2000 [10] | 1, types of surgery mentioned | 1 | | Ozaki et al., 1996 [24] | 1, types of surgery mentioned | 1 | | Staals et al., 2006 [25] | 1, types of surgery mentioned | 0 | | van Maldegem et al., 2014 [26] | 1, types of surgery mentioned | 1 |
|
|
| (f) |
| | Author, year | Disclosure |
| | Andreou et al., 2011 [15] | 1 | | Angelini et al., 2012 [16] | 1 | | Briccoli et al., 2002 [17] | 0 | | Cho et al., 2011 [18] | 1 | | de Camargo et al., 2010 [19] | 1 | | Donati et al., 2010 [20] | 1 | | Donati et al., 2005 [21] | 1 | | Gitelis et al., 1981 [22] | 0 | | Mavrogenis et al., 2013 [23] | 1 | | Mitchell et al., 2000 [10] | 1 | | Ozaki et al., 1996 [24] | 0 | | Staals et al., 2006 [25] | 0 | | van Maldegem et al., 2014 [26] | 1 |
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