Research Article

Intraoperative Radiotherapy in the Management of Locally Recurrent Extremity Soft Tissue Sarcoma

Table 1

Baseline patient characteristics at time of reresection and IORT ( = 26).

Patient characteristicNumber of patients (%)

Age
 Median51 years
 Range12–76 years
 ≤181 (4%)
 19–5012 (46%)
 >5013 (50%)

Gender
 Female15 (58%)
 Male11 (42%)

Site
 Lower extremity11 (42%)
 Upper extremity15 (58%)

Histology
 Undifferentiated pleomorphic sarcoma7 (27%)
 Synovial sarcoma5 (19%)
 Liposarcoma4 (15%)
 Fibrosarcoma3 (11.5%)
 Spindle cell sarcoma3 (11.5%)
 Leiomyosarcoma1 (4%)
 Malignant peripheral nerve sheath tumor1 (4%)
 Rhabdomyosarcoma1 (4%)
 Soft tissue sarcoma, NOS1 (4%)

T stage
 T112 (46%)
 T214 (54%)

Depth
 Superficial4 (15%)
 Deep22 (85%)

Grade (FNCLCC)
 16 (23%)
 26 (23%)
 314 (54%)

AJCC group stage
 I6 (23%)
 II11 (42%)
 III5 (19%)
 IV4 (15%)

Initial local recurrence type
 Single20 (77%)
 Multiple6 (23%)

Time to initial recurrence
 Median17 mo.
 Range3–199 mo.