Research Article

Intraoperative Radiotherapy in the Management of Locally Recurrent Extremity Soft Tissue Sarcoma

Table 2

Treatment characteristics.

Treatment characteristicNumber of patients (%)

Surgical margins
 Positive12 (46%)
 Close (≤2 mm)7 (27%)
 Negative7 (27%)

Radiation therapy
 EBRT prior to recurrence15 (58%)
  Median dose (range)63 Gy (25–72)
 EBRT following IORT11 (42%)
  Median dose (range)52 Gy (22–60)
 IORT cone size
  Median7 cm
  Range3–10 cm
 IORT dose
  Median15 Gy
  Range10–18 Gy

Chemotherapy ( = 24)
 As part of initial therapy6 (25%)
 Peri-IORT13 (54%)
Peri-IORT chemotherapy schedule
 Pre-IORT alone6 (25%)
 Post-IORT alone6 (25%)
 Pre- & Post-IORT1 (4%)