Intraoperative Radiotherapy in the Management of Locally Recurrent Extremity Soft Tissue Sarcoma

Table 3

Incidence of grade 3 acute and late toxicity.

Toxicity	Acute; Number of patients (%)	Late; Number of patients (%)
Wound complications
EBRT prior to recurrence	2 (8%)	3 (15%)
EBRT following IORT	1 (4%)	1 (4%)
Limb/joint dysfunction
EBRT prior to recurrence	1 (4%)	3 (12%)
EBRT following IORT	2 (8%)	3 (12%)
Total	6 (23%)	8 (31%)

Five of the 6 patients with grade 3 acute toxicity also had late toxicity of the same type, and 7 patients had multiple grade 3 toxicities.