Research Article
Age, Tumor Characteristics, and Treatment Regimen as Event Predictors in Ewing: A Children’s Oncology Group Report
Table 3
Estimated risk coefficients on univariate analysis for 1444 patients treated in consecutive COG studies.
| Factor | Characteristic | Relative risk | 95% confidence interval | value compared reference | Global value |
| Age yrs. (ref. <9) | | | | | 0.0000 | | 10–17 | 1.34 | 1.08–1.66 | 0.0090 | | | 18+ | 2.35 | 1.78–3.11 | 0.0000 | | Primary site (ref. pelvis) | | | | | 0.0002 | | Nonpelvic tumor | 0.70 | 0.52–0.93 | 0.0140 | | | Extraosseous | 0.52 | 0.37–0.72 | 0.0000 | | Gender (ref. male) | | | | | 0.3404 | | Female | 0.92 | 0.77–1.10 | 0.08 | | Treatment (ref. standard timing) | | | | | 0.0002 | | Non-I/E | 1.65 | 1.31–2.09 | 0.0000 | | | Intensive timing | 0.82 | 0.64–1.06 | 0.1260 | | Tumor size, cm (ref. <8) | | | | | 0.0002 | | 9–12 cm | 1.26 | 0.96–1.65 | 0.0990 | | | >13 cm | 1.98 | 1.45–2.70 | 0.0000 | |
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