miR-125b and miR-100 Are Predictive Biomarkers of Response to Induction Chemotherapy in Osteosarcoma

Table 2

Clinical and pathological data of osteosarcoma patients for validation study.

Case number	Gender	Age	Location	Histologic type	Neoadjuvant chemotherapy	Viable cells
Number 1	Male	19	Tibia	Osteoblastic	MTX + DOX + CDDP	0–10%	NED
Number 2	Female	9	Femur	Osteoblastic	MTX + DOX + CDDP	0%	CDF
Number 3	Female	9	Tibia	Chondroblastic	MTX + DOX + CDDP	0–10%	DOD
Number 4	Female	14	Femur	Osteoblastic	MTX + DOX + CDDP	0	CDF
Number 5	Female	15	Femur	Osteoblastic	MTX + DOX + CDDP	0–10%	DOD
Number 6	Female	9	Tibia	Osteoblastic	MTX + DOX + CDDP	0%	NED
Number 7	Male	17	Femur	Osteoblastic	MTX + DOX + CDDP	0–10%	CDF
Number 8	Female	17	Tibia	Osteoblastic	MTX + DOX + CDDP	1%	CDF
Number 9	Female	11	Femur	Chondroblastic	MTX + DOX + CDDP	7%	CDF
Number 10	Male	13	Femur	Osteoblastic	MTX + DOX + CDDP	0–10%	DOD
Number 11	Male	16	Femur	Chondroblastic	MTX + DOX + CDDP	0–10%	DOD
Number 12	Female	13	Tibia	Osteoblastic	MTX + DOX + CDDP	60–70%	DOD
Number 13	Male	22	Femur	Osteoblastic	MTX + DOX + CDDP	30%	DOD
Number 14	Male	18	Femur	Osteoblastic	MTX + DOX + CDDP	60–70%	NED
Number 15	Male	14	Tibia	Osteoblastic	MTX + DOX + CDDP	50–60%	CDF
Number 16	Male	13	Femur	Osteoblastic	MTX + DOX + CDDP	30–40%	AWD
Number 17	Male	9	Femur	Chondroblastic	MTX + DOX + CDDP	30–40%	NED
Number 18	Female	10	Femur	Chondroblastic	MTX + DOX + CDDP	70%	CDF
Number 19	Male	17	Ilium	Fibroblastic	MTX + DOX + CDDP		DOD
Number 20	Male	15	Tibia	Osteoblastic	MTX + DOX + CDDP	50–60%	NED

A: Probability of viable cells was pathologically evaluated by surgical specimen. B: patients with disease progression in diagnostic imaging by computed tomography and magnetic resource imaging. C: CDF: continuously disease-free, DOD: died of disease, NED: no evidence of disease, and AWD: alive with disease.