Sarcoma

Research Article

miR-125b and miR-100 Are Predictive Biomarkers of Response to Induction Chemotherapy in Osteosarcoma

Table 3

Genes commonly regulated by miRNA-100 and miRNA-125b.
Accession numberSymbolGene titleBiological function
Upregulated genes   
 NM_006868RAB31RAB31, member RAS oncogene familyNucleotide binding
 NM_012241SIRT5Sirtuin (silent mating type information regulation 2 homolog) 5NAD+ ADP-ribosyltransferase activity
 NM_001142864PIEZO1Piezo-type mechanosensitive ion channel component 1Cation channel activity
 NM_002383MAZMYC-associated zinc finger proteinMetal ion binding
 NM_004997MYBPHMyosin binding protein HStructural constituent of muscle
 NM_000261MYOCMyocilin, trabecular meshwork inducible glucocorticoid responseStructural molecule activity
 NM_014292CBX6Chromobox homolog 6Chromatin binding
 NM_145267C6orf57Chromosome 6 open reading frame 57Unknown
Downregulated genes   
 NM_000576IL1BInterleukin 1, betaCytokine activity
 NM_014510PCLOpiccolo (presynaptic cytomatrix protein)Calcium ion binding
 NM_001017402LAMB3Laminin, beta 3Structural molecule activity
 NM_004864GDF15Growth differentiation factor 15Cytokine activity
 NM_000379XDHXanthine dehydrogenaseNucleotide binding
 NM_182507KRT80Keratin 80Structural molecule activity
 NM_213602SIGLEC15Sialic acid binding Ig-like lectin 15Unknown
 NM_005565LCP2Lymphocyte cytosolic protein 2Unknown