A Therapeutic Role for Survivin in Mitigating the Harmful Effects of Ionizing Radiation

Figure 3

TreadScan software was used to track functional ability. Prior to beginning the radiation protocol, both groups of mice performed similarly on the treadmill. However, following 50 Gy of radiation, YFP mice showed a significant decrease in (a) instant run speed and (b) overall speed, while performance of survivin mice remained relatively unaffected. Student’s -test was used to compare the groups and demonstrated a significant result. Data are mean ± s.d.; per group. Student’s -test: = 0.05, = 0.01. indicates significance.

(a)

(b)