Research Article
Immediate versus Delayed Sarcoma Reconstruction: Impact on Outcomes
Table 1
Characteristics of the study population by reconstructive type.
| | | Delayed ( = 17) | Immediate ( = 53) | Total ( = 70) | value1 |
| | Age | | | | 0.3613 | | Mean (SD) | 59.8 (16.9) | 64.3 (18.0) | 63.2 (17.8) | | | Median (range) | 66.0 (17.0–81.0) | 67.0 (22.0–94.0) | 66.5 (17.0–94.0) | |
| | Sex, female (%) | 11 (64.7%) | 33 (62.3%) | 44 (62.9%) | 1.0000 |
| | Diagnosis, n | | | | 0.4740 | | Myxofibrosarcoma | 5 (29.4%) | 7 (13.2%) | 12 (17.1%) | | | Synovial sarcoma | 1 (5.9%) | 5 (9.4%) | 6 (8.6%) | | | Leiomyosarcoma | 2 (11.8%) | 4 (7.5%) | 6 (8.6%) | | | Liposarcoma | 2 (11.8%) | 3 (5.7%) | 5 (7.1%) | | | Sarcoma NOS | 2 (11.8%) | 4 (7.5%) | 6 (8.6%) | | | Myxoid chondrosarcoma | 1 (5.9%) | 0 (0.0%) | 1 (1.4%) | | | Myxoid liposarcoma | 2 (11.8%) | 2 (3.8%) | 4 (5.7%) | | | Fibrous histiocytoma | 0 (0.0%) | 5 (9.4%) | 5 (7.1%) | | | Fibrosarcoma | 0 (0.0%) | 4 (7.5%) | 4 (5.7%) | | | Pleomorphic sarcoma | 0 (0.0%) | 7 (13.2%) | 7 (10.0%) | | | Spindle cell sarcoma | 1 (5.9%) | 3 (5.7%) | 4 (5.7%) | | | Pleomorphic liposarcoma | 1 (5.9%) | 0 (0.0%) | 1 (1.4%) | | | Dermatofibrosarcoma protuberans | 0 (0.0%) | 1 (1.9%) | 1 (1.4%) | | | Angiosarcoma, high grade | 0 (0.0%) | 1 (1.9%) | 1 (1.4%) | | | Giant cell rich extraosseous osteosarcoma | 0 (0.0%) | 1 (1.9%) | 1 (1.4%) | | | Fibroblastic sarcoma | 0 (0.0%) | 1 (1.9%) | 1 (1.4%) | | | Epithelioid angiosarcoma | 0 (0.0%) | 2 (3.8%) | 2 (2.9%) | | | Osteosarcoma | 0 (0.0%) | 1 (1.9%) | 1 (1.4%) | | | Neurofibrosarcoma | 0 (0.0%) | 1 (1.9%) | 1 (1.4%) | | | Epitheloid sarcoma | 0 (0.0%) | 1 (1.9%) | 1 (1.4%) | |
| | Neoadjuvant chemotherapy, n | 8 (47.1%) | 14 (26.4%) | 22 (31.4%) | 0.1381 |
| | Neoadjuvant radiation, n | 14 (82.4%) | 34 (64.2%) | 48 (68.6%) | 0.2324 |
| | Neoadjuvant radiation dosage, gy | | | | 0.1167 | | Mean (SD) | 39.9 (19.7) | 30.0 (23.3) | 32.4 (22.7) | | | Median | 50.0 (0.0–50.4) | 45.0 (0.0–50.4) | 50.0 (0.0–50.4) | |
| | Intraoperative radiation, n | 9 (52.9%) | 16 (30.2%) | 25 (35.7%) | 0.1443 |
| | Intraoperative radiation dosage, gy | | | | 0.1240 | | Mean (SD) | 6.8 (6.7) | 4.0 (6.2) | 4.7 (6.4) | | | Median (Range) | 10.0 (0.0–15.0) | 0.0 (0.0–17.5) | 0.0 (0.0–17.5) | |
| | Obesity, n | 8 (47.1%) | 7 (13.2%) | 15 (21.4%) | 0.0060 |
| | Peripheral Vascular Disease, n | 0 (0.0%) | 1 (1.9%) | 1 (1.4%) | 1.0000 |
| | Coronary Artery Disease, n | 1 (5.9%) | 5 (9.4%) | 6 (8.6%) | 1.0000 |
| | Diabetes, n | 4 (23.5%) | 4 (7.5%) | 8 (11.4%) | 0.0911 |
| | Current smoker, n | 1 (5.9%) | 5 (9.4%) | 6 (8.6%) | 1.0000 |
| | Alcohol abuse, n | 0 (0.0%) | 1 (1.9%) | 1 (1.4%) | 1.0000 |
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Fisher’s exact test was used for categorical variables and two sample t-test was used for continuous variables. ( significant). gy = gray.
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