Research Article

Routes to Diagnosis for Suspected Sarcoma: The Impact of Symptoms and Clinical Findings on the Diagnostic Process

Table 3

Patient reported initial symptoms.

Initial symptomSarcomas ()
(%)
Other malignancies ()
(%)
Benign ()
(%)

Noticed lump67 (65.7)27 (39.7)194 (51.7)
Noticed indentation of the skin1 (1.0)0 (0.0)1 (0.3)
Mobile lump0 (0.0)2 (2.9)2 (0.5)
Noticed swelling7 (6.9)7 (10.3)34 (9.1)
Soft lump1 (1.0)1 (1.5)2 (0.5)
Lump with discharge0 (0.0)0 (0.0)1 (0.3)
Hard lump4 (3.9)0 (0.0)8 (2.1)
Previously removed lump recurred6 (5.9)0 (0.0)3 (0.8)
Noticed skin change/wound4 (3.9)3 (4.4)3 (0.8)
Itching1 (1.0)0 (0.0)4 (1.1)
Redness1 (1.0)0 (0.0)5 (1.3)
Pain27 (26.5)24 (35.3)135 (36.0)
Bother/pain related to pressure on lump6 (5.9)0 (0.0)13 (3.5)
Night pain1 (1.0)0 (0.0)5 (1.3)
Pain or stiffness in the morning0 (0.0)0 (0.0)1 (0.3)
Pain related to movement5 (4.9)4 (5.9)23 (6.1)
Tenderness6 (5.9)4 (5.9)37 (9.9)
Radiating pain4 (3.9)1 (1.5)12 (3.2)
Sensation of tightness2 (2.0)2 (2.9)3 (0.8)
Reduced strength2 (2.0)0 (0.0)1 (0.3)
Sensibility disturbances3 (2.9)1 (1.5)8 (2.1)
Sensation of heaviness0 (0.0)0 (0.0)1 (0.3)
Reduced ability to practice sports1 (1.0)1 (1.5)8 (2.1)
Problems with walking4 (3.9)1 (1.5)11 (2.9)
Reduction of movement ability0 (0.0)1 (1.5)11 (2.9)
Started after a trauma6 (5.9)8 (11.8)34 (9.1)
Started after exercise1 (1.0)0 (0.0)5 (1.3)
Clicking sound from joint0 (0.0)0 (0.0)2 (0.5)
Slipping sensation in joint0 (0.0)0 (0.0)2 (0.5)
Joint locking0 (0.0)0 (0.0)5 (1.3)
Sensation of snap in muscle0 (0.0)2 (2.9)1 (0.3)
Fever0 (0.0)0 (0.0)1 (0.3)
Hot flushes0 (0.0)0 (0.0)2 (0.5)
Sleep disturbances0 (0.0)0 (0.0)3 (0.8)
Weight loss0 (0.0)2 (2.9)3 (0.8)
Lump discovered by others5 (4.9)1 (1.5)19 (5.1)
Noticed blood in underwear1 (1.0)0 (0.0)0 (0.0)
Bluish skin1 (1.0)0 (0.0)2 (0.5)
Fatigue0 (0.0)2 (2.9)8 (2.1)
Occurred in relation to pregnancy0 (0.0)0 (0.0)3 (0.8)
Dizziness0 (0.0)1 (1.5)2 (0.5)
Occurred after mononucleosis0 (0.0)0 (0.0)1 (0.3)
Hematuria2 (2.0)1 (1.5)0 (0.0)
Flank pain2 (2.0)0 (0.0)0 (0.0)
Fracture1 (1.0)1 (1.5)0 (0.0)
Occurred after insect bite1 (1.0)0 (0.0)1 (0.3)
Yellow skin0 (0.0)1 (1.5)0 (0.0)
Shortness of breath0 (0.0)1 (1.5)0 (0.0)
Constipation0 (0.0)0 (0.0)1 (0.3)
Night sweat0 (0.0)1 (1.5)0 (0.0)
Intermittent pain0 (0.0)0 (0.0)9 (2.4)
Headache0 (0.0)0 (0.0)1 (0.3)
Warm skin0 (0.0)0 (0.0)1 (0.3)

Patients may have more than one initial presenting symptom.