Clinical Study
Concurrent Imatinib and Radiation Therapy for Unresectable and Symptomatic Desmoid Tumors
Table 2
Selected previous studies of desmoid tumors treated with imatinib or radiation therapy alone.
| Manuscript | Toxicity | Local control |
| Imatinib alone | Heinrich et al. 2006 [8] | ≥50% grade 3 | 36.8% at 1 year | Chugh et al. 2010 [7] | ≥9.8% grade 3/4 | 66% at 1 year | Penel et al. 2011 [9] | 45% grade 3 | 67% at 1 year |
| Radiation alone | Nuyttens et al. 2000 [10] | 22.8% total | 78% at 6 years | Guadagnolo et al. 2008 [11] | 10.5% moderate, 4.3% severe | 68% at 10 years | Keus et al. 2013 [19] | 4.5% grade 3 | 81.5% at 3 years |
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